In-Cell NMR and EPR Spectroscopy of Biomacromolecules
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F14%3A00074124" target="_blank" >RIV/00216224:14740/14:00074124 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1002/anie.201311320/abstract" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/anie.201311320/abstract</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/anie.201311320" target="_blank" >10.1002/anie.201311320</a>
Alternative languages
Result language
angličtina
Original language name
In-Cell NMR and EPR Spectroscopy of Biomacromolecules
Original language description
The dream of cell biologists is to be able to watch biological macromolecules perform their duties in the intracellular environment of live cells. Ideally, the observation of both the location and the conformation of these macromolecules with biophysicaltechniques is desired. The development of many fluorescence techniques, including super-resolution fluorescence microscopy, has significantly enhanced our ability to spot proteins and other molecules in the crowded cellular environment. However, the observation of their structure and conformational changes while they attend their business is still very challenging. In principle, NMR and EPR spectroscopy can be used to investigate the conformation and dynamics of biological macromolecules in living cells. The development of in-cell magnetic resonance techniques has demonstrated the feasibility of this approach.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA13-28310S" target="_blank" >GA13-28310S: Evolutionary conserved structural features of centromeric and telomeric DNA</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Angewandte Chemie International Edition
ISSN
1433-7851
e-ISSN
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Volume of the periodical
53
Issue of the periodical within the volume
39
Country of publishing house
DE - GERMANY
Number of pages
15
Pages from-to
10300-10314
UT code for WoS article
000342760700004
EID of the result in the Scopus database
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