Impact of cognitive stimulation on ripples within human epileptic and non-epileptic hippocampus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00081244" target="_blank" >RIV/00216224:14740/15:00081244 - isvavai.cz</a>
Alternative codes found
RIV/68081731:_____/15:00451683 RIV/00216305:26220/15:PU114918 RIV/00159816:_____/15:00063979
Result on the web
<a href="http://www.biomedcentral.com/content/pdf/s12868-015-0184-0.pdf" target="_blank" >http://www.biomedcentral.com/content/pdf/s12868-015-0184-0.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12868-015-0184-0" target="_blank" >10.1186/s12868-015-0184-0</a>
Alternative languages
Result language
angličtina
Original language name
Impact of cognitive stimulation on ripples within human epileptic and non-epileptic hippocampus
Original language description
Background: Until now there has been no way of distinguishing between physiological and epileptic hippocampal ripples in intracranial recordings. In the present study we addressed this by investigating the effect of cognitive stimulation on interictal high frequency oscillations in the ripple range (80-250 Hz) within epileptic (EH) and non-epileptic hippocampus (NH). Methods: We analyzed depth EEG recordings in 10 patients with intractable epilepsy, in whom hippocampal activity was recorded initially during quiet wakefulness and subsequently during a simple cognitive task. Using automated detection of ripples based on amplitude of the power envelope, we analyzed ripple rate (RR) in the cognitive and resting period, within EH and NH. Results: Compared to quiet wakefulness we observed a significant reduction of RR during cognitive stimulation in EH, while it remained statistically marginal in NH. Further, we investigated the direct impact of cognitive stimuli on ripples (i.e.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BMC Neuroscience
ISSN
1471-2202
e-ISSN
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Volume of the periodical
16
Issue of the periodical within the volume
july
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
"nestránkováno"
UT code for WoS article
000358412200001
EID of the result in the Scopus database
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