Detection of Minimal Residual Disease in Mantle Cell Lymphoma. Establishment of Novel Eight-Color Flow Cytometry Approach
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00082240" target="_blank" >RIV/00216224:14740/15:00082240 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/15:00063173
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1002/cyto.b.21210/epdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/cyto.b.21210/epdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/cytob.21210" target="_blank" >10.1002/cytob.21210</a>
Alternative languages
Result language
angličtina
Original language name
Detection of Minimal Residual Disease in Mantle Cell Lymphoma. Establishment of Novel Eight-Color Flow Cytometry Approach
Original language description
Backround: Minimal residual disease (MRD) detection is an essential tool for therapy response assessment in a considerable number of hematooncologic disorders including mantle cell lymphoma (MCL). Flow cytometry (FCM) ranks among the most effective approaches which allow rapid sample processing and compete successfully with highly sensitive molecular methods like polymerase chain reaction (PCR). Since FCM is ordinarily applied to detect MRD in B-lineage diseases like chronic lymphocytic leukemia (CLL),a similar method could be used in MCL. We decided to test our novel 8-color FCM approach in MCL MRD detection. Methods: Employing an 8-color FCM protocol designed by us, the expression of 24 selected surface antigens in a cohort of 30 patients with newlydiagnosed leukemic MCL and 20 normal controls were compared to one another to establish markers that can reliably distinguish normal B lymphocytes from the MCL population.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cytometry Part B: Clinical Cytometry
ISSN
1552-4949
e-ISSN
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Volume of the periodical
88
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
92-100
UT code for WoS article
000350302000003
EID of the result in the Scopus database
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