Detection of p53 Gene by Using Genomagnetic Assay Combined with Carbon Nanotube Modified Disposable Sensor Technology

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00085531" target="_blank" >RIV/00216224:14740/15:00085531 - isvavai.cz</a>

Alternative codes found

RIV/68081707:_____/15:00456710

Result on the web

<a href="http://onlinelibrary.wiley.com/doi/10.1002/elan.201400731/epdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/elan.201400731/epdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/elan.201400731" target="_blank" >10.1002/elan.201400731</a>

Result language

angličtina

Original language name

Detection of p53 Gene by Using Genomagnetic Assay Combined with Carbon Nanotube Modified Disposable Sensor Technology

Original language description

Electrochemical monitoring of DNA hybridization related to p53 gene sequence was investigated using genomagnetic assay combined with single walled carbon nanotube (SWCNT) modified pencil graphite electrodes (PGEs). The hybridization was performed eitherat magnetic beads (MB) surface or in solution. The enhanced guanine signal was obtained using SWCNT-PGEs compared to one obtained by unmodified PGEs. The selectivity of genomagnetic assay was tested under optimum conditions. The DLs were calculated as 0.88 mu M and 0.11 mu M for hybridization performed at MB surface and solution, respectively. This selective, practical and cost effective genomagnetic assay combined with SWCNT-PGEs is reported herein for the first time.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CG - Electrochemistry

OECD FORD branch

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Project

<a href="/en/project/GAP206%2F11%2F1638" target="_blank" >GAP206/11/1638: Novel electrochemical sensors and sensing techniques for the analysis of nucleic acids structure and interactions</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Electroanalysis

ISSN

1040-0397

e-ISSN

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Volume of the periodical

27

Issue of the periodical within the volume

7

Country of publishing house

DE - GERMANY

Number of pages

8

Pages from-to

1579-1586

UT code for WoS article

000357408900006

EID of the result in the Scopus database

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