Hydrolytic stability of end-linked hydrogels from PLGA-PEG-PLGA macromonomers terminated by alpha,omega-itaconyl groups

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F16%3A00093660" target="_blank" >RIV/00216224:14740/16:00093660 - isvavai.cz</a>

Alternative codes found

RIV/00216305:26620/16:PU118384

Result on the web

<a href="http://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C5RA26222D#!divAbstract" target="_blank" >http://pubs.rsc.org/en/Content/ArticleLanding/2016/RA/C5RA26222D#!divAbstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/c5ra26222d" target="_blank" >10.1039/c5ra26222d</a>

Result language

angličtina

Original language name

Hydrolytic stability of end-linked hydrogels from PLGA-PEG-PLGA macromonomers terminated by alpha,omega-itaconyl groups

Original language description

Biodegradable amphiphilic PLGA-PEG-PLGA triblock copolymers end-terminated with itaconic acid (ITA) having reactive double bonds were synthesized by ring opening polymerization. The prepared alpha,omega-itaconyl-PLGA- PEG-PLGA telechelic macromonomers were additionally covalently crosslinked under an inert atmosphere by blue light irradiation without the use of a further cross-linker resulting in end-linked polymeric networks. The effects of the ITA amount attached to the alpha,omega-itaconyl-PLGA-PEG-PLGA copolymers and the crosslinking time on swelling behaviours and hydrolytic stability of the prepared well-defined polymeric network were investigated. Physicochemical properties were characterized by proton and carbon nuclear magnetic resonance spectroscopy (H-1 NMR, C-13 NMR), proton nuclear magnetic resonance relaxometry, attenuated total reflectance Fourier transformed infrared spectroscopy (ATR-FTIR) and thermogravimetric analysis (TGA).

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CF - Physical chemistry and theoretical chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

RSC Advances

ISSN

2046-2069

e-ISSN

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Volume of the periodical

6

Issue of the periodical within the volume

20

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

16808-16816

UT code for WoS article

000370710600090

EID of the result in the Scopus database

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