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Sleep Deprivation and Structural Fluctuations in White Matter

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F16%3A00094116" target="_blank" >RIV/00216224:14740/16:00094116 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sleep Deprivation and Structural Fluctuations in White Matter

  • Original language description

    Day-to-day stability of neuronal communication is essential for undistorted reconstructions of our perceptions, thoughts and emotions. To a great extent, such stability relies on the regulated delivery of molecules and organelles from neuronal cell bodies to discrete axonal compartments via axonal transport (AT). Sleep deprivation is one of the potential sources of altered AT, which is likely to have an impact on structural properties of white matter assessed in vivo with magnetic resonance imaging (MRI). The current study tested the hypothesis that short-term sleep deprivation, namely a restriction of sleep to 4 hours per nigth for 8 nights, will induce structural fluctuations in white matter, as identified by serial MRI. Multi-modal images of brain structure were acquired every two days (for 10 days) in two groups of young men: (1) Sleep-deprived group (n=12); and (2) Control (no sleep deprivation) group (n=12).

  • Czech name

  • Czech description

Classification

  • Type

    V<sub>souhrn</sub> - Summary research report

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2016

  • Confidentiality

    C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.

Data specific for result type

  • Number of pages

    3

  • Place of publication

    Brno

  • Publisher/client name

    Child Mind Institute

  • Version