The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F17%3A00100465" target="_blank" >RIV/00216224:14740/17:00100465 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26620/17:PU121273
Result on the web
<a href="https://link.springer.com/article/10.1007%2Fs00396-016-3983-7" target="_blank" >https://link.springer.com/article/10.1007%2Fs00396-016-3983-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00396-016-3983-7" target="_blank" >10.1007/s00396-016-3983-7</a>
Alternative languages
Result language
angličtina
Original language name
The effect of hydroxyapatite particle size on viscoelastic properties and calcium release from a thermosensitive triblock copolymer
Original language description
Well-defined "smart" injectable hydrogel based on hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(lactic acid-co-glycolic acid) (PLA/PGA) copolymer (PLGA-PEG-PLGA) gelling at the body temperature was modified by bioactive hydroxyapatite (HAp) in the form of micro-, nano-, and core-shell particles (mu-HAp, n-HAp, and CS-x, respectively) to be applicable as calcium delivery system in bone regeneration. Viscoelastic moduli increased with HAp content as expected. Whereas systems containing mu-HAp or CS-x particles maintained two sol-gel and gel-sol phase transitions, the n-HAp containing system showed only one sol-gel phase transition due to the strong interactions between polymer chain and the n-HAp surface. In vitro, studies proved the controlled uniform release of calcium cations from both CS-x and n-HAp over the 9-day period without any initial burst release.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
COLLOID AND POLYMER SCIENCE
ISSN
0303-402X
e-ISSN
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Volume of the periodical
295
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
107-115
UT code for WoS article
000392135800011
EID of the result in the Scopus database
2-s2.0-84997284789