Neurochemical Responses to Chromatic and Achromatic Stimuli in the Human Visual Cortex
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F18%3A00101973" target="_blank" >RIV/00216224:14740/18:00101973 - isvavai.cz</a>
Result on the web
<a href="http://journals.sagepub.com/doi/abs/10.1177/0271678X17695291?journalCode=jcba" target="_blank" >http://journals.sagepub.com/doi/abs/10.1177/0271678X17695291?journalCode=jcba</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/0271678X17695291" target="_blank" >10.1177/0271678X17695291</a>
Alternative languages
Result language
angličtina
Original language name
Neurochemical Responses to Chromatic and Achromatic Stimuli in the Human Visual Cortex
Original language description
In the present study we aimed at determining the metabolic responses of the human visual cortex during the presentation of chromatic and achromatic stimuli, known to preferentially activate two separate clusters of neuronal populations (called “blobs” and “interblobs”) with distinct sensitivity to color or luminance features. Since blobs and interblobs have different cytochrome-oxidase (COX) content and micro-vascularization level (i.e., different capacities for glucose oxidation), different functional metabolic responses during chromatic vs. achromatic stimuli may be expected. The stimuli were optimized to evoke a similar load of neuronal activation as measured by the bold oxygenation level dependent (BOLD) contrast. Metabolic responses were assessed using functional 1H MRS at 7 T in 12 subjects. During both chromatic and achromatic stimuli, we observed the typical increases in glutamate and lactate concentration, and decreases in aspartate and glucose concentration, that are indicative of increased glucose oxidation. However, within the detection sensitivity limits we did not observe any difference between metabolic responses elicited by chromatic and achromatic stimuli. We conclude that the higher energy demands of activated blobs and interblobs are supported by similar increases in oxidative metabolism despite the different capacities of these neuronal populations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
<a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Cerebral Blood Flow and Metabolism
ISSN
0271-678X
e-ISSN
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Volume of the periodical
38
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
347-359
UT code for WoS article
000424060500013
EID of the result in the Scopus database
2-s2.0-85041617129