Neurochemical and BOLD responses during neuronal activation measured in the human visual cortex at 7 Tesla

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00082816" target="_blank" >RIV/00216224:14740/15:00082816 - isvavai.cz</a>
Result on the web
<a href="http://www.nature.com/jcbfm/journal/v35/n4/full/jcbfm2014233a.html" target="_blank" >http://www.nature.com/jcbfm/journal/v35/n4/full/jcbfm2014233a.html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/jcbfm.2014.233" target="_blank" >10.1038/jcbfm.2014.233</a>

Result language
angličtina
Original language name
Neurochemical and BOLD responses during neuronal activation measured in the human visual cortex at 7 Tesla
Original language description
Several laboratories have consistently reported small concentration changes in lactate, glutamate, aspartate, and glucose in the human cortex during prolonged stimuli. However, whether such changes correlate with blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI) signals have not been determined. The present study aimed at characterizing the relationship between metabolite concentrations and BOLD-fMRI signals during a block-designed paradigm of visual stimulation. Functional magnetic resonance spectroscopy (fMRS) and fMRI data were acquired from 12 volunteers. A short echo-time semiLASER localization sequence optimized for 7 Tesla was used to achieve full signal-intensity MRS data. The group analysis confirmed that during stimulation lactate and glutamate increased by 0.26 +/- 0.06 mu mol/g (similar to 30%) and 0.28 +/- 0.03 mu mol/g (similar to 3%), respectively, while aspartate and glucose decreased by 0.20 +/- 0.04 mu mol/g (similar to 5%) and 0.19 +
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—

Project
<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)