Current Computational Approaches for the Development of Anti-HIV Inhibitors: An Overview

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F19%3A00113284" target="_blank" >RIV/00216224:14740/19:00113284 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.2174/1381612825666190911160244" target="_blank" >http://dx.doi.org/10.2174/1381612825666190911160244</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2174/1381612825666190911160244" target="_blank" >10.2174/1381612825666190911160244</a>

Result language

angličtina

Original language name

Current Computational Approaches for the Development of Anti-HIV Inhibitors: An Overview

Original language description

Background: Today, HIV-1 infection has become an extensive problem to public health and a greater challenge to all working researchers throughout the world. Since the beginning of HIV-1 virus, several antiviral therapeutic agents have been developed at various stages to combat HIV-1 infection. But, the many of antiviral drugs are on the platform of drug resistance and toxicology issues, needs an urgent constructive investigation for the development of productive and protective therapeutics to make an improvement of individual life suffering with viral infection. As developing a novel agent is very costly, challenging and time taking route in the recent times. Methods: The review summarized about the modern approaches of computational aided drug discovery to developing a novel inhibitor within a short period of time and less cost. Results: The outcome suggests on the premise of reported information that the computational drug discovery is a powerful technology to design a defensive and fruitful therapeutic agents to combat HIV-1 infection and recover the lifespan of suffering one. Conclusion: Based on survey of the reported information, we concluded that the current computational approaches is highly supportive in the progress of drug discovery and controlling the viral infection.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30104 - Pharmacology and pharmacy

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Current Pharmaceutical Design

ISSN

1381-6128

e-ISSN

—

Volume of the periodical

25

Issue of the periodical within the volume

31

Country of publishing house

AE - UNITED ARAB EMIRATES

Number of pages

16

Pages from-to

3390-3405

UT code for WoS article

000496934200010

EID of the result in the Scopus database

2-s2.0-85075814376