Game of thrones among AUXIN RESPONSE FACTORs—over 30 years of MONOPTEROS research

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F23%3A00131248" target="_blank" >RIV/00216224:14740/23:00131248 - isvavai.cz</a>

Result on the web

<a href="https://academic.oup.com/jxb/advance-article/doi/10.1093/jxb/erad272/7224461" target="_blank" >https://academic.oup.com/jxb/advance-article/doi/10.1093/jxb/erad272/7224461</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/jxb/erad272" target="_blank" >10.1093/jxb/erad272</a>

Result language

angličtina

Original language name

Game of thrones among AUXIN RESPONSE FACTORs—over 30 years of MONOPTEROS research

Original language description

For many years, research has been carried out with the aim of understanding the mechanism of auxin action, its biosynthesis, catabolism, perception, and transport. One central interest is the auxin-dependent gene expression regulation mechanism involving AUXIN RESPONSE FACTOR (ARF) transcription factors and their repressors, the AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) proteins. Numerous studies have been focused on MONOPTEROS (MP)/ARF5, an activator of auxin-dependent gene expression with a crucial impact on plant development. This review summarizes over 30 years of research on MP/ARF5. We indicate the available analytical tools to study MP/ARF5 and point out the known mechanism of MP/ARF5-dependent regulation of gene expression during various developmental processes, namely embryogenesis, leaf formation, vascularization, and shoot and root meristem formation. However, many questions remain about the auxin dose-dependent regulation of gene transcription by MP/ARF5 and its isoforms in plant cells, the composition of the MP/ARF5 protein complex, and, finally, all the genes under its direct control. In addition, information on post-translational modifications of MP/ARF5 protein is marginal, and knowledge about their consequences on MP/ARF5 function is limited. Moreover, the epigenetic factors and other regulators that act upstream of MP/ARF5 are poorly understood. Their identification will be a challenge in the coming years.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10605 - Developmental biology

Project

<a href="/en/project/EF16_019%2F0000738" target="_blank" >EF16_019/0000738: Centre for Experimental Plant Biology</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Experimental Botany

ISSN

0022-0957

e-ISSN

1460-2431

Volume of the periodical

74

Issue of the periodical within the volume

22

Country of publishing house

GB - UNITED KINGDOM

Number of pages

18

Pages from-to

6904-6921

UT code for WoS article

001166999200001

EID of the result in the Scopus database

2-s2.0-85179671840