Evolutionary Divergence in Hymenoptera and Lepidoptera Telomerase RNAs: A Shift from the Norm in Animal TR Biogenesis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F24%3A00138958" target="_blank" >RIV/00216224:14740/24:00138958 - isvavai.cz</a>
Result on the web
<a href="https://meetings.embo.org/event/24-telomere" target="_blank" >https://meetings.embo.org/event/24-telomere</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Evolutionary Divergence in Hymenoptera and Lepidoptera Telomerase RNAs: A Shift from the Norm in Animal TR Biogenesis
Original language description
Unlike typical animal TRs, which are transcribed by RNA Polymerase II, the TRs in Hymenoptera and Lepidoptera insects display characteristics similar to TRs in plants and ciliates, transcribed by RNA Polymerase III under the control of type 3 promoters. This significant deviation in TR biogenesis challenges the previously assumed monophyletic origin of TRs in animals and suggests an evolutionary shift in TR type and biogenesis within Arthropods. This discovery not only questions the uniformity of TR evolution across animals but also highlights the evolutionary flexibility in telomere biology, particularly in the context of insect genomic stability and telomere maintenance mechanisms.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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