AFM application across the life sciences field and its combination with special techniques
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F25%3A00142219" target="_blank" >RIV/00216224:14740/25:00142219 - isvavai.cz</a>
Result on the web
<a href="https://afmbiomed.org/Barcelona-2025-scientific-program.aspx" target="_blank" >https://afmbiomed.org/Barcelona-2025-scientific-program.aspx</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
AFM application across the life sciences field and its combination with special techniques
Original language description
These approaches enhance the obtained data by integrating AFM (topography, mechanics) with information from other techniques within the same region of interest. It provides key insights into the structural and biomechanical behaviour of biological systems in their native state and physiological environments, enabling a deeper understanding of complex processes such as biomolecule imaging and cell mechanics. AFM’s versatility is further enhanced through its combination with other techniques, such as Raman spectroscopy, fluorescence microscopy, and scanning electron microscopy (SEM). While Raman spectroscopy provides precise chemical characterization, fluorescence microscopy enables the specific localization of desired interactions. Moreover, the correlative AFM-in-SEM enables precise in-situ data correlation, combining nanoscale topography with different information from SEM channels. Additionally, advanced AFM techniques, such as Fluid AFM, enable nanomanipulation, including single-cell nano-injection, expanding its applications in biomedical research. These combined methodologies provide a deeper understanding across a wide range of life sciences, including cellular processes, biomaterial interactions, and disease-related mechanical alterations, making AFM an excellent and useful tool for modern biological and biomedical research.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů