Oxidative stress and metabolic syndrome in obese patients

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F06%3A00004401" target="_blank" >RIV/00216275:25310/06:00004401 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Oxidative stress and metabolic syndrome in obese patients
Original language description
The aim of this study was to evaluate the effect of oxidative stress in obese people with metabolic syndrome (MS). Free radical plasma levels and total antioxidant capacity were determined in obese people fulfilling at least 3 criteria of MS (MS, 15 patients), obese ones without MS (OB, 18 patients), and in 48 healthy controls (C). Free radical concentration was determined by direct method based on chlorophyllin acceptance of electrons, total antioxidant capacity using the kit TAS (Randox, UK). Plasma levels of glucose, triglycerides, HDL-ch, LDL-ch, fibrinogen, uric acid and BMI, waistline and blood pressure were followed. The highest level of free radicals was found in patients with metabolic syndrome. MS: 8.68 +- 3.70 mmol/l vs OB: 6.34 +- 1.80 mmol/l (p0.05) vs C: 4.71 +- 0.77 mmol/l (p0.01). Total antioxidant capacity was low in all groups. MS: 0.91 +- 0.12 mmol/l vs OB: 0.73 +- 0.10 mmol/l (p0.05) vs C: 0.81 +- 0.09 mmol/l (p0.05). In MS group significantly (p0.05) higher levels
Czech name
Oxidační stres a metabolický syndrom u obesních pacientů
Czech description
Oxidační stres a metabolický syndrom u obesních pacientů

Project
<a href="/en/project/OC%20124" target="_blank" >OC 124: Screening of phytochemical compounds effective in protection against cardiovascular disease</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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