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Evaluation of oxidative stress and inflammation in obese adults with metabolic syndrome.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F08%3A00006270" target="_blank" >RIV/00216275:25310/08:00006270 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/08:00001294 RIV/00216208:11150/08:00106735

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Evaluation of oxidative stress and inflammation in obese adults with metabolic syndrome.

  • Original language description

    Background: Obesity and metabolic syndrome increase the risk of cardiovascular morbidity and mortality. Oxidative stress seems to be involved in pathophysiology of diabetes and cardiovascular complications of metabolic syndrome. The aim of our study wasto evaluate the level of oxidative stress and inflammation in obese adults with and without metabolic syndrome. Methods: Oxidative stress and inflammation markers (total amount of free radicals, malondialdehyde, allantoin, a1antiproteinase, GSSG/GSH ratio, hsCRP, fibrinogen), total antioxidant capacity and lipid standardized a-tocopherol were determined in obese people fulfilling at least 3 criteria of metabolic syndrome according to NCEP ATP III (20 patients), in obese people without metabolic syndrome(20 patients) and in 48 healthy controls. Results: Oxidative stress and inflammation markers were significantly elevated in the obese individuals, especially those exhibiting metabolic syndrome. According to multidimensional statistical

  • Czech name

    Zhodnocení oxidačního stresu a zánětu u obezních osob s metabolickým syndromem

  • Czech description

    Zhodnocení oxidačního stresu a zánětu u obezních osob s metabolickým syndromem

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/OC%20124" target="_blank" >OC 124: Screening of phytochemical compounds effective in protection against cardiovascular disease</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical Chemistry and Laboratory Medicine

  • ISSN

    1434-6621

  • e-ISSN

  • Volume of the periodical

    46

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    7

  • Pages from-to

    499-505

  • UT code for WoS article

  • EID of the result in the Scopus database