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In vitro Inhibition of Cholinesterases by Carbamates ? A Kinetic Study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F07%3A00006313" target="_blank" >RIV/00216275:25310/07:00006313 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    In vitro Inhibition of Cholinesterases by Carbamates ? A Kinetic Study

  • Original language description

    Kinetics and mechanism of inhibition of in vitro hydrolyses of acetylcholine and acetylthiocholine by carbamates were studied in a batch reactor at 25 oC, pH 8 and ionic strength of 0.11 M. Every hydrolysis was monitored by 3 ? 4 independent methods. Allstudied hydrolyses can be described by the model competitive inhibition with an irreversible step (k3). A table of obtained average values of rate constants and discussion of the results are presented.

  • Czech name

    In-vitro inhibice cholinesterasy pomocí karbamátů - Kinetická studie

  • Czech description

    Byly studovány kinetika a mechanizmus inhibice in vitro hydrolýz acetylcholinu a acetylthiocholinu ve vsádkovém reaktoru při 25 oC, pH 8 aiontové síle 0.11 M. Každá hydrolýza byla sledována 3 ? 4 nezávislými metodami. Všechny studované hydrolýzy mohou být popsány modelem kompetitivní inhibice s nevratným krokem (k3). Jsou uvedeny tabulka průměrných hodnot rychlostních konstant a diskuse výsledků.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Zeitschrift fuer Naturforschung C-A Journal of Biosciences

  • ISSN

    0939-5075

  • e-ISSN

  • Volume of the periodical

    62c

  • Issue of the periodical within the volume

    N

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    3

  • Pages from-to

    305-307

  • UT code for WoS article

  • EID of the result in the Scopus database