Effects of functional monomers on retention behavior of small and large molecules in monolithic capillary columns at isocratic and gradient conditions

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F11%3A39892629" target="_blank" >RIV/00216275:25310/11:39892629 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1002/jssc.201100174" target="_blank" >http://dx.doi.org/10.1002/jssc.201100174</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jssc.201100174" target="_blank" >10.1002/jssc.201100174</a>

Result language

angličtina

Original language name

Effects of functional monomers on retention behavior of small and large molecules in monolithic capillary columns at isocratic and gradient conditions

Original language description

The polarity of (poly)methacrylate monolithic capillary columns was varied by using alkylmethacrylate monomers with butyl, cyclohexyl, 2-ethylhexyl, lauryl, and stearyl functional groups in the polymerization mixture. The hydrodynamic properties, as wellas the retention characteristics in RP-LC of small molecules (alkylbenzenes) and of proteins under gradient elution conditions were studied. The RP selectivity depends on the type of alkyl chain in methacrylate monomer; however, there was no direct correlation between the size of the monomer molecule and methylene or aromatic selectivity of the monlithic column. The lowest selectivity was found for column based on lauryl methacrylate monomer. On the other hand, butyl methacrylate column shows high phenyl selektivity and the column with stearyl methacrylate possesses the highest methylene selectivity for small molecules.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

<a href="/en/project/GA203%2F07%2F0641" target="_blank" >GA203/07/0641: New analytical methods in combined high-capacity phase separation systems</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Separation Science

ISSN

1615-9306

e-ISSN

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Volume of the periodical

34

Issue of the periodical within the volume

16

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

2054-2062

UT code for WoS article

000295189400012

EID of the result in the Scopus database

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