Thermodynamic dissociation constants of risedronate using spectrophotometric and potentiometric pH-titration

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F12%3A39883555" target="_blank" >RIV/00216275:25310/12:39883555 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.2478/s11532-011-0150-3" target="_blank" >http://dx.doi.org/10.2478/s11532-011-0150-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2478/s11532-011-0150-3" target="_blank" >10.2478/s11532-011-0150-3</a>

Result language

angličtina

Original language name

Thermodynamic dissociation constants of risedronate using spectrophotometric and potentiometric pH-titration

Original language description

The mixed dissociation constants were determined at different ionic strengths I = 0.02 to 0.26 M KCl and of 25?C and 37?C using pH-spectrophotometric and pH-potentiometric titration methods. Determination of group parameters L0, HT might lead to false estimate of common parameters pKa and therefore make the computational strategy important. Comparing two programs, ESAB and HYPERQUAD, the ESAB led to a better fitness of potentiometric titration curve. The thermodynamic dissociation constants pKTa were estimated by a nonlinear regression of (pKa, I) data and a Debye-Hückel equation at 25?C and 37?C, pKTa,2 = 2.37(1) and 2.44(1), pKTa,3 = 6.29(3) and 6.26(1), pKTa,4 = 7.48(1) and 7.46(2) and pKTa,5 = 9.31(7) and 8.70(3)at 25?C and 37?C using pH-spectroscopic data and pKTa,2 = 2.48(3) and 2.43(1), pKTa,3= 6.12(2) and 6.10(2), pKTa,4 = 7.25(2) and 7.23(1) and pKTa,5 = 12.04(5) and 11.81(2) at 25?C and 37?C.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CF - Physical chemistry and theoretical chemistry

OECD FORD branch

—

Project

<a href="/en/project/NS9831" target="_blank" >NS9831: Optimization of laboratory examinations in endocrinology using multivariate statistics</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Central European Journal of Chemistry

ISSN

1895-1066

e-ISSN

—

Volume of the periodical

10

Issue of the periodical within the volume

2

Country of publishing house

PL - POLAND

Number of pages

15

Pages from-to

338-353

UT code for WoS article

000299703800009

EID of the result in the Scopus database

—