Antibacterial and Herbicidal Activity of Ring-Substituted 2-Hydroxynaphthalene-1-carboxanilides

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896488" target="_blank" >RIV/00216275:25310/13:39896488 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16170/13:43872231 RIV/62157124:16370/13:43872231 RIV/62157124:16810/13:43872231

Result on the web

<a href="http://dx.doi.org/10.3390/molecules18089397" target="_blank" >http://dx.doi.org/10.3390/molecules18089397</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/molecules18089397" target="_blank" >10.3390/molecules18089397</a>

Result language

angličtina

Original language name

Antibacterial and Herbicidal Activity of Ring-Substituted 2-Hydroxynaphthalene-1-carboxanilides

Original language description

In this study, a series of twenty-two ring-substituted 2-hydroxynaphthalene1-carboxanilides were prepared and characterized. Primary in vitro screening of the synthesized compounds was performed against Staphylococcus aureus, three methicillin-resistantS. aureus strains, Mycobacterium marinum, M. kasasii, M. smegmatis and M. avium paratuberculosis. The compounds were also tested for their activity related to inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. 2-Hydroxy-N-phenylnaphthalene-1-carboxanilide and 2-hydroxy-N-(3trifluoromethylphenyl)naphthalene-1-carboxamide showed MIC = 26.0 ?mol/L against methicillin-resistant S. aureus and (IC50 = 29 ?mol/L) were the most active PET inhibitors. Some of tested compounds showed the antibacterial and antimycobacterial activity against the tested strains comparable or higher than the standards ampicillin or isoniazid. Thus, for example, 2-hydroxy-N-(3-nitrophenyl)naphthalene-1carboxamide show

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CC - Organic chemistry

OECD FORD branch

—

Project

<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecules

ISSN

1420-3049

e-ISSN

—

Volume of the periodical

18

Issue of the periodical within the volume

8

Country of publishing house

CH - SWITZERLAND

Number of pages

23

Pages from-to

9397-9419

UT code for WoS article

000330304100044

EID of the result in the Scopus database

—