Antibacterial and Herbicidal Activity of Ring-Substituted 3-Hydroxynaphthalene-2-carboxanilides

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67179843%3A_____%2F13%3A00425628" target="_blank" >RIV/67179843:_____/13:00425628 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16170/13:43872233 RIV/62157124:16370/13:43872233 RIV/62157124:16810/13:43872233

Result on the web

<a href="http://dx.doi.org/10.3390/molecules18077977" target="_blank" >http://dx.doi.org/10.3390/molecules18077977</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/molecules18077977" target="_blank" >10.3390/molecules18077977</a>

Result language

angličtina

Original language name

Antibacterial and Herbicidal Activity of Ring-Substituted 3-Hydroxynaphthalene-2-carboxanilides

Original language description

In this study, a series of twenty-two ring-substituted 3-hydroxy-N-phenylnaphthalene-2-carboxanilides were prepared and characterized. The compounds were tested for their activity related to inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the synthesized compounds was also performed against four Staphylococcus strains and against two mycobacterial species. 3-Hydroxy-N-(2-methoxyphenyl)naphthalene-2-carboxamide showed high biological activity (MIC = 55.0 mu mol/L) against S. aureus as well as methicillin-resistant strains. N-(2-Fluorophenyl)-3-hydroxynaphthalene-2-carboxamide showed higher activity (MIC = 28.4 mu mol/L) against M. marinum than the standard isoniazid and3-hydroxy-N-(4-nitrophenyl) naphthalene-2-carboxamide expressed higher activity (MIC = 13.0 mu mol/L) against M. kansasii than the standard isoniazid. Cytotoxicity assay of effective antimicrobial compounds was performed using the human m

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EH - Ecology - communities

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecules

ISSN

1420-3049

e-ISSN

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Volume of the periodical

18

Issue of the periodical within the volume

7

Country of publishing house

CH - SWITZERLAND

Number of pages

21

Pages from-to

7977-7997

UT code for WoS article

000330300900040

EID of the result in the Scopus database

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