Electrochemical mechanism and sensitive assay of antiretroviral drug Abacavir in biological sample using multiwalled carbon nanotube modified pyrolytic graphite electrode

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F14%3A39898285" target="_blank" >RIV/00216275:25310/14:39898285 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.jelechem.2013.11.012" target="_blank" >http://dx.doi.org/10.1016/j.jelechem.2013.11.012</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jelechem.2013.11.012" target="_blank" >10.1016/j.jelechem.2013.11.012</a>

Result language

angličtina

Original language name

Electrochemical mechanism and sensitive assay of antiretroviral drug Abacavir in biological sample using multiwalled carbon nanotube modified pyrolytic graphite electrode

Original language description

Multiwalled carbon nanotube modified edge plane pyrolytic graphite electrode (MWCNT/EPPGE) was developed and implemented for the determination of antiretroviral drug Abacavir using differential pulse adsorptive stripping voltammetry (DP AdSV). Cyclic voltammogram showed two oxidation peaks located at +0.91 V and +1.10 V on (MWCNT/EPPGE). Dependency of peak potential and peak current on pH was investigated as details. The oxidation potentials affected by the pH indicating protons are involved in the electrochemical oxidation of Abacavir. Mass transport to the electrode surface was found as a combination of diffusion and adsorption which was concluded by studying the potential scan rate dependency of both peak currents. The oxidation mechanism was proposed using the obtained data and discussed. A large enhancement in both of the peak currents was observed with applying an accumulation step presenting the effect of adsorption. Peak currents showed a linear relation upon the Abacavir conce

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CG - Electrochemistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Electroanalytical Chemistry

ISSN

1572-6657

e-ISSN

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Volume of the periodical

712

Issue of the periodical within the volume

January

Country of publishing house

CH - SWITZERLAND

Number of pages

7

Pages from-to

178-184

UT code for WoS article

000330749300025

EID of the result in the Scopus database

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