Organs of BALB/c mice can be injured in course of tularemia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F14%3A39898412" target="_blank" >RIV/00216275:25310/14:39898412 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/14:43875214 RIV/00216305:26620/14:PU127105
Result on the web
<a href="http://biomed.papers.upol.cz/artkey/bio-201404-0010_Organs_of_BALB_c_mice_can_be_injured_in_course_of_tularemia.php#.VK-Z7snz-p4" target="_blank" >http://biomed.papers.upol.cz/artkey/bio-201404-0010_Organs_of_BALB_c_mice_can_be_injured_in_course_of_tularemia.php#.VK-Z7snz-p4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2013.006" target="_blank" >10.5507/bp.2013.006</a>
Alternative languages
Result language
angličtina
Original language name
Organs of BALB/c mice can be injured in course of tularemia
Original language description
Background: Francisella tularensis is a biological agent exploitable for bioterrorism and biological warfare purposes due to serious pathogenic progression and easy dissemination. Despite intensive research in the past, some adverse consequences remain unclear. One consequence of this pathogen is oxidative stress. Aims: The aim of this study was to undertake ex vivo assays for monitoring the disease in mice and increase our knowledge of the oxidative stress induced by tularemia. Methods: The mouse BALB/c model was chosen and the animals were infected by a dose 104 CFU of F. tularensis. After five days, the animals were euthanized. Blood immediately processed in plasma, spleen and liver were sampled from the cadavers. Oxidative stress markers, cytokinesand histopathological were undertaken. Results: There was a significant link between oxidative stress and tularemia. Particularly elevated levels of malondialdehyde and decreased levels of low molecular weight antioxidants were found in
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical Papers
ISSN
1213-8118
e-ISSN
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Volume of the periodical
158
Issue of the periodical within the volume
4
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
5
Pages from-to
557-561
UT code for WoS article
000347173200010
EID of the result in the Scopus database
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