Immunosensors in Early Cancer Diagnostics: From Individual to Multiple Biomarker Assays
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F18%3A39911283" target="_blank" >RIV/00216275:25310/18:39911283 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2174/0929867324666171121101245" target="_blank" >http://dx.doi.org/10.2174/0929867324666171121101245</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2174/0929867324666171121101245" target="_blank" >10.2174/0929867324666171121101245</a>
Alternative languages
Result language
angličtina
Original language name
Immunosensors in Early Cancer Diagnostics: From Individual to Multiple Biomarker Assays
Original language description
Cancer is a widespread disease characterized by high mortality. To improve the survival rate or facilitate effective therapy, accurate and reliable diagnosis at an early stage is needed. For this reason, there is a continuous push to develop sensitive methods which can be used in cancer diagnosis. Current diagnosis relies on the quantification of cancer biomarkers defined as molecules that are measurable in body fluids or tissues and indicate a change in physiological processes with subsequent pathological manifestations. This contribution reviews recent developments in the area of electrochemical immunosensors applicable for the detection of cancer biomarkers that occur in a wide concentration range including extremely low levels, which are typical for the early stage of the disease. A summary of various antibody labels used for biomarker analysis and combined with electrochemical detection is presented. The potential of multiple biomarker analysis, with its indisputable clinical impact for accurate diagnosis, is also highlighted.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10620 - Other biological topics
Result continuities
Project
<a href="/en/project/GA15-16549S" target="_blank" >GA15-16549S: Development of ultrasensitive magneto-immunoassay based on quantum dots/antibody probes for simultaneous electrochemical detection of cancer markers.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Medicinal Chemistry
ISSN
0929-8673
e-ISSN
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Volume of the periodical
25
Issue of the periodical within the volume
33
Country of publishing house
AE - UNITED ARAB EMIRATES
Number of pages
15
Pages from-to
3973-3987
UT code for WoS article
000448120700003
EID of the result in the Scopus database
2-s2.0-85055633444