Synthesis, characterization and cytotoxic activity of vanadocene dithiocarbamate complexes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F19%3A39914733" target="_blank" >RIV/00216275:25310/19:39914733 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/19:10393719 RIV/00216208:11310/19:10393719
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0020169318311745" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0020169318311745</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ica.2018.10.010" target="_blank" >10.1016/j.ica.2018.10.010</a>

Result language
angličtina
Original language name
Synthesis, characterization and cytotoxic activity of vanadocene dithiocarbamate complexes
Original language description
This study describes synthesis of water-soluble vanadocene and 1,1'-dimethylvanadocene compounds bearing dithiocarbamate ligands. All prepared compounds were characterized by analytical and spectroscopic methods. The structure of [(eta(5)-C5H4Me)(2)V{S2CN(CH2)(4)O}]Cl was determined by single-crystal X-ray diffraction analysis. The cytotoxicity of the synthesized compounds was investigated on human leukemia cells MOLT-4. The derivatives bearing cyclic dithiocarbamates show considerably stronger activity than reported for cisplatin.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10402 - Inorganic and nuclear chemistry

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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