Mobile phase effects in reversed-phase and hydrophilic interaction liquid chromatography

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F20%3A39916295" target="_blank" >RIV/00216275:25310/20:39916295 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Mobile phase effects in reversed-phase and hydrophilic interaction liquid chromatography
Original language description
The ultimate target of High Performance Liquid Chromatography (HPLC), like of other analytical separation techniques, is the resolution and determination of sample components. The retention, the separation selectivity and the chromatographic efficiency control the resolution and the separation quality in liquid chromatography (LC). The development of efficient chromatographic columns has experienced remarkable success in the last two decades. Some of the modern types of efficient stationary phases, including the sub-2µm-particle, core-shell, monolithic and micropillar-array columns, challenge the correct definition of the volumes of the stationary and the mobile phase, between which the solute distribute during the migration along the column. Adopting a phase volume convention can mitigate the problems due to possible mixing of the adsorption and partition mechanism and to the selective preferential adsorption of mobile phase components in the stationary phase.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2020
Confidentiality
C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.

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