CONSTITUTIVE MODEL OF VASCULAR SMOOTH MUSCLE CELLS DETERMINED USING COMPUTATIONAL SIMULATION
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F04%3APU47294" target="_blank" >RIV/00216305:26210/04:PU47294 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
CONSTITUTIVE MODEL OF VASCULAR SMOOTH MUSCLE CELLS DETERMINED USING COMPUTATIONAL SIMULATION
Original language description
It is well known that vascular smooth muscle cells (VSMCs) play important role not only in vascular tone but also in arterial remodelling, healing and growth. Determination of mechanical properties of these cells is very important for understanding not only the physiology of VSMCs themselves but also the basic physiology, pathology, and mechanics of arterial wall. In the present study, a constitutive model of VSMCs of contractile and synthetic phenotypes is determined using FEM computational simulationof tension test of isolated cells. Material of the cells was modelled as homogeneous and isotropic using Mooney-Rivlin five-parameter hyperelastic strain energy density function. The model was loaded similarly to the real experiment by micropipet displacement.
Czech name
CONSTITUTIVE MODEL OF VASCULAR SMOOTH MUSCLE CELLS DETERMINED USING COMPUTATIONAL SIMULATION
Czech description
It is well known that vascular smooth muscle cells (VSMCs) play important role not only in vascular tone but also in arterial remodelling, healing and growth. Determination of mechanical properties of these cells is very important for understanding not only the physiology of VSMCs themselves but also the basic physiology, pathology, and mechanics of arterial wall. In the present study, a constitutive model of VSMCs of contractile and synthetic phenotypes is determined using FEM computational simulationof tension test of isolated cells. Material of the cells was modelled as homogeneous and isotropic using Mooney-Rivlin five-parameter hyperelastic strain energy density function. The model was loaded similarly to the real experiment by micropipet displacement.
Classification
Type
D - Article in proceedings
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Engineering Mechanics 2004
ISBN
80-85918-88-9
ISSN
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e-ISSN
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Number of pages
2
Pages from-to
167-168
Publisher name
Institute of Thermomechanics, AS CR
Place of publication
Praha
Event location
Svratka
Event date
May 10, 2004
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
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