Mechanical properties of vascular smooth muscle cells

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F05%3APU55159" target="_blank" >RIV/00216305:26210/05:PU55159 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Mechanical properties of vascular smooth muscle cells

Original language description

Mechanical properties of vascular smooth muscle cells are closely related to their physiological function within the arterial wall (blood pressure regulation, arterial remodelling, healing and growth. Mechanical stimuli represent a very important factorinfluencing cellular processes and functions. The knowledge about mechanical properties of cells is necessary for understanding how cells response to mechanical stress and strain. A lot of experiments are carried out with the aim to determine mechanicalproperties of cells (tensile test, compression test, micropipette aspiration test, indentation test). A 3D finite element model of adherent cell for computational simulation of indentation test is presented in this paper. Our model considers all significant structural cellular components, i.e. actin cortex, deep cytoskeleton, cytoplasma and nucleus. The geometry model is based on experimental observations of a spreading fibroblast. Actin cortex was modelled as a thin membrane meshed with

Czech name

Mechanical properties of vascular smooth muscle cells

Czech description

Mechanical properties of vascular smooth muscle cells are closely related to their physiological function within the arterial wall (blood pressure regulation, arterial remodelling, healing and growth. Mechanical stimuli represent a very important factorinfluencing cellular processes and functions. The knowledge about mechanical properties of cells is necessary for understanding how cells response to mechanical stress and strain. A lot of experiments are carried out with the aim to determine mechanicalproperties of cells (tensile test, compression test, micropipette aspiration test, indentation test). A 3D finite element model of adherent cell for computational simulation of indentation test is presented in this paper. Our model considers all significant structural cellular components, i.e. actin cortex, deep cytoskeleton, cytoplasma and nucleus. The geometry model is based on experimental observations of a spreading fibroblast. Actin cortex was modelled as a thin membrane meshed with

Type

D - Article in proceedings

CEP classification

JR - Other machinery industry

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Proceedings of the 7th International Scientific Conference Applied Mechanics 2005

ISBN

80-214-2373-0

ISSN

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e-ISSN

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Number of pages

1

Pages from-to

65-65

Publisher name

VUT Brno

Place of publication

Hrotovice

Event location

Hrotovice

Event date

Mar 29, 2005

Type of event by nationality

EUR - Evropská akce

UT code for WoS article

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