DOUBLE TENSEGRITY FE MODEL OF CELL USED IN SIMULATION OF ITS INDENTATION TEST

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F06%3APU63193" target="_blank" >RIV/00216305:26210/06:PU63193 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

DOUBLE TENSEGRITY FE MODEL OF CELL USED IN SIMULATION OF ITS INDENTATION TEST

Original language description

Mechanical stimuli represent a very important factor influencing physiological and pathological processes in live tissues. Since these processes are initiated on the cellular level, it is necessary to focus on the eukaryotic cell as a basic structural unit of a tissue. A major interest in the cell mechanics is the regulation of cellular functions by mechanical forces, it means: how the mechanical stimulus is transduced into biochemical response. This process is known as mechanotransduction. The key rolein this process plays the cytoskeleton. The cytoskeleton is a closely interwoven network of actin, tubulin, and intermediate filaments that modulates cell sensitivity to mechanical stimuli by adapting its structure to accommodate prolonged mechanical strains [1] Cytoskeletal integrity is important for detection and transduction of mechanical strain and cellular elasticity. For investigation of principles of mechanotransduction in living animal cells is necessary to study of cell as a me

Czech name

MKP model buňky s dvojitou tensegritní strukturou cytoskeletu

Czech description

Příspěvek uvádí simulaci vtlačovací zkoušky izolované hladké svylové buňky pomocí MKP modelu, obsahujícího tensegritní strukturu modelující kortikální, hluboký a jaderný cytoskelet. Výsledky ukazují schopnost realistického modelování chování buňky pomocíuvedeného modelu.

Type

D - Article in proceedings

CEP classification

BO - Biophysics

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Human biomechanics 2006

ISBN

80-214-3232-2

ISSN

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e-ISSN

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Number of pages

5

Pages from-to

138-142

Publisher name

Brno University of Technology, Institute of Solid Mechanics, Mechatronics and Biomechanics

Place of publication

Hrotovice

Event location

Hrotovice

Event date

Nov 13, 2006

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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