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Postnatal Development of the Urine Cortisol/Creatinine Ratio in the Dog

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F08%3APU77856" target="_blank" >RIV/00216305:26210/08:PU77856 - isvavai.cz</a>

  • Alternative codes found

    RIV/62157124:16270/08:10013351

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Postnatal Development of the Urine Cortisol/Creatinine Ratio in the Dog

  • Original language description

    The objective of this study was to determine the cortisol to creatinine ratio in urine of growing puppies between birth and the age of 8 weeks. Beagle puppies (n = 14) of three litters were used. The puppies of litters 1 and 2 were from a research breeding facility and litter 3 from a dog breeder. They were nursed by their dams and obtained extra puppy food from the 4th week of age. The puppies were weighed weekly. Morning urine was sampled at the age of up to 48 h, and 7, 14, 21, 24, 35, and 56 days. Urine cortisol was measured using the RIA method, and creatinine was determined using a diagnostic kit. The urine cortisol to creatinine ratio (UCCR) was calculated. The body mass of all puppies increased more than ten times, and most of its increments from week to week were significant (p < 0.05 to p < 0.001). The UCCR for litters 1 and 2 as against litter 3 showed no significant differences and therefore the results were pooled. Thus no effect of the rearing environment upon this indica

  • Czech name

    Postnatal Development of the Urine Cortisol/Creatinine Ratio in the Dog

  • Czech description

    Cílem studie bylo stanovit poměr kortisolu a kreatininu (UCCR) v moči rostoucích štěňat od narození do věku osmi týdnů. Použita byla štěňata plemene bígl (n = 14), ze tří vrhů. Vrhy 1 a 2 byly odchovávány ve výzkumném zařízení, vrh 3 u chovatele. Všechnaštěňata byla kojena a od 4. týdne přikrmována. Jednou týdně byla vážena. Ranní moč byla odebírána ve věku do 48 h, a poté 7., 14., 21., 35. a 56. den po narození. Koncentrace kortisolu v moči byla měřena pomocí RIA metody, ke stanovení kreatininu byl použit diagnostický kit. Z výsledků byl vypočítáván poměr kortisolu a kreatininu. Hmotnost štěňat vzrostla v pokusném údobí více než 10 x, její vzestupy byly vesměs významné (p ? 0.05 až p ? 0.001). V poměru kortisolu a kreatininu nebyly mezi vrhy nalezenyrozdíly, proto byly všechny hodnoty sloučeny. Vliv různého prostředí se tedy na UCCR neprojevil. UCCR štěňat do 48 h po narození byl 44,32 +- 30,47 x 10-6 . Následujíc

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EG - Zoology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    ACTA VETERINARIA BRNO

  • ISSN

    0001-7213

  • e-ISSN

  • Volume of the periodical

    77

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    5

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database