Immunoreactive Cortisol Measurement in Canine Urine and its Validity in Hyperadrenocorticism Diagnosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F00%3A00000325" target="_blank" >RIV/62157124:16170/00:00000325 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Immunoreactive Cortisol Measurement in Canine Urine and its Validity in Hyperadrenocorticism Diagnosis

Original language description

The aim of this study was to compare two methods of immunoreactive cortisol determination in urine and an assesssment of the validity of urine cortisol/creatinine ratio (UCCR) in dogs. The UCCR was measured in three groups of dogs: (1) healthy dogs, (2)dogs with hyperadrenocorticism and (3) dogs suffering from other diseases presented with polyuria and polydipsia (PU/PD). All cortisol measurements in urine were performed using two methods: (1) fluorescence polarisation immunoassay (FPIA) with urine extraction and (2) radioimmunoassay without urine extraction. Paired results of 30 cortisol measurement and 30 UCCR were compared using the Wilcoxon test. It was proved that the difference between the two methods (i. e., FPIA with urine extraction and RIA without urine extraction) were highly statistically significant (p < 0,01). While in the cortisol measurement using the FPIA with urine extraction the median of the UCCR amounted to 18, 53 x 10-6, in the RIA without extraction it was 37,83

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GJ - Diseases and animal vermin, veterinary medicine

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2000

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Veterinaria (Brno)

ISSN

0001-7213

e-ISSN

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Volume of the periodical

69

Issue of the periodical within the volume

41

Country of publishing house

XX - stateless person

Number of pages

7

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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