Simulation of size-dependent aerosol deposition in a realistic model of the upper human airways

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F17%3APU125209" target="_blank" >RIV/00216305:26210/17:PU125209 - isvavai.cz</a>

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S0021850216302968?via%3Dihub" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0021850216302968?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jaerosci.2017.10.007" target="_blank" >10.1016/j.jaerosci.2017.10.007</a>

Result language

angličtina

Original language name

Simulation of size-dependent aerosol deposition in a realistic model of the upper human airways

Original language description

An Eulerian internally mixed aerosol model is used for predictions of deposition inside a realistic cast of the human upper airways. The model, formulated in the multi-species and compressible framework, is solved using the sectional discretization of the droplet size distribution function to accurately capture size-dependent aerosol dynamics such as droplet drift, gravitational settling and diffusion. These three mechanisms are implemented in a consistent way in the model, guaranteeing that the total droplet mass as given by the droplet size distribution is always equal to the total droplet mass due to the mass concentration fields. To validate the model, we simulate monodisperse glycerol aerosol deposition inside the lung cast, for which experimental data is available. Provided that an adequate computational mesh is used and an adequate boundary treatment for the inertial deposition velocity, excellent agreement is found with the experimental data. Finally, we study the size-dependent deposition inside the lung cast for a polydisperse aerosol with droplet sizes ranging from the nanometer scale to beyond the micrometer scale. The typical V-shape’ deposition curve is recovered. The aim of this paper is to 1) provide an overview of the Eulerian aerosol dynamics model and method, to 2) validate this method in a relevant complex lung geometry and to 3) explore the capabilities of the method by simulating polydisperse aerosol deposition.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20303 - Thermodynamics

Project

<a href="/en/project/GA16-23675S" target="_blank" >GA16-23675S: Multiscale laminar, transitional and turbulent accelerating and decelerating flow in human respiratory tract with aerosol transport and deposition</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

JOURNAL OF AEROSOL SCIENCE

ISSN

0021-8502

e-ISSN

1879-1964

Volume of the periodical

115

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

17

Pages from-to

29-45

UT code for WoS article

000415846200003

EID of the result in the Scopus database

2-s2.0-85032441763