The effect of synovial fluid composition, speed and load on frictional behaviour of articular cartilage

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F20%3APU135856" target="_blank" >RIV/00216305:26210/20:PU135856 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/1996-1944/13/6/1334" target="_blank" >https://www.mdpi.com/1996-1944/13/6/1334</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ma13061334" target="_blank" >10.3390/ma13061334</a>

Result language

angličtina

Original language name

The effect of synovial fluid composition, speed and load on frictional behaviour of articular cartilage

Original language description

Articular cartilage ensures smooth motion of natural synovial joints operating at very low friction. However, number of patients suffering from joint diseases, usually associated with cartilage degradation, continuously increases. Therefore, an understanding of cartilage tribological behaviour is of great interest in order to minimize its degradation, preserving the reliable function of the joints. The aim of the present study is to provide a comprehensive comparison of frictional behaviour of articular cartilage, focusing on the effect of synovial fluid composition (i), speed (ii), and load (iii). The experiments were realized using pin-on-plate tribometer with reciprocating motion. The articular cartilage pin was loaded against smooth glass plate while the tests consisted of loading and unloading phases in order to enable cartilage rehydration. Various model fluids containing albumin, γ-globulin, hyaluronic acid, and phospholipids were prepared in two different concentrations simulating physiologic and osteoarthritic synovial fluid. Two different speeds, 5 mm/s and 10 mm/s were applied and the tests were carried out under 5 N and 10 N. It was found that protein based solutions exhibit nearly no difference in friction coefficient, independently of the concentration of the constituents. However, the behaviour is considerably changed when adding hyaluronic acid and phospholipids. Especially when interacting with γ-globulin, friction coefficient decreased substantially. In general, an important role of the interaction of fluid constituents was observed. On the other hand, a limited effect of speed was detected for most of the model fluids. Finally, it was shown that elevated load leads to lower friction which well corresponds to previous observations. Further study should concentrate on specific explored phenomena focusing on the detailed statistical evaluation.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20301 - Mechanical engineering

Project

<a href="/en/project/GA20-00483S" target="_blank" >GA20-00483S: An investigation of synovial fluid viscosupplementation and its impact on friction and lubrication</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Materials

ISSN

1996-1944

e-ISSN

—

Volume of the periodical

13

Issue of the periodical within the volume

6

Country of publishing house

CH - SWITZERLAND

Number of pages

16

Pages from-to

1-16

UT code for WoS article

000529208000073

EID of the result in the Scopus database

2-s2.0-85082691720