IMPACT OF FORMALDEHYDE ON MECHANICAL PROPERTIES OF ATHEROSCLEROTIC CAROTID ARTERIES
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F20%3APU138087" target="_blank" >RIV/00216305:26210/20:PU138087 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
IMPACT OF FORMALDEHYDE ON MECHANICAL PROPERTIES OF ATHEROSCLEROTIC CAROTID ARTERIES
Original language description
Atherosclerosis is a life threatening cardiovascular disease causing lipoprotein accumulation within intima layer of artery wall and thus its thickening. Later stages are characterized by plaque formation with a lipid core separated from lumen by fibrous cap. In case of carotid arteries (CA), rupture of the plaque often results in a stroke. Detailed understanding of mechanical properties of atherosclerotic arteries and their components is essential for improvement of computer models used for prediction of plaque rupture. Samples of atherosclerotic CA from carotid endarterectomy were kept either in saline solution or in formaldehyde solution and then underwent uniaxial tensile testing in two directions. Statistical analysis of the obtained stress-strain responses shows that formaldehyde treatment of the tissue increases significantly the mean stiffness and reduces the dispersion.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10610 - Biophysics
Result continuities
Project
<a href="/en/project/GA18-13663S" target="_blank" >GA18-13663S: COMPUTATIONAL MODELLING OF RUPTURE RISK OF ATHEROSCLEROTIC PLAQUES IN CAROTID ARTERIES</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů