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Atherosclerotic plaque characteristics and the risk of brain ischemia during internal carotid artery stenting

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13450%2F20%3A43895902" target="_blank" >RIV/44555601:13450/20:43895902 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.csnn.eu/en/journals/czech-and-slovak-neurology-and-neurosurgery/2020-1-4/atherosclerotic-plaque-characteristics-and-the-risk-of-brain-ischemia-dur-ing-internal-carotid-artery-stent-ing-121156" target="_blank" >https://www.csnn.eu/en/journals/czech-and-slovak-neurology-and-neurosurgery/2020-1-4/atherosclerotic-plaque-characteristics-and-the-risk-of-brain-ischemia-dur-ing-internal-carotid-artery-stent-ing-121156</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.14735/amcsnn202084" target="_blank" >10.14735/amcsnn202084</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Atherosclerotic plaque characteristics and the risk of brain ischemia during internal carotid artery stenting

  • Original language description

    Aim: The aim of a prospective multicenter study was to determine whether the risk of developing a new ischemic brain lesion on control MRI is dependent on some of the characteristics of atherosclerotic plaque detected by duplex sonography, MRI and CTA. Materials and methods: Patients with internal carotid artery stenosis (70-95%) indicated for carotid angioplasty and stenting (CAS) were consecutively included in the prospective observational study. All enrolled patients underwent neurological and physical examinations, duplex sonographic examination of the carotid arteries with evaluation of the structure of atherosclerotic plaque in the ultrasound B-mode, CTA of the cervical and cerebral arteries and MRI of the neck and brain. The univariate and multivariate logistic regression analyses were performed to identify factors affecting the risk of the onset of brain ischemia following CAS. Results: A total of 121 patients (93 males, age 70.5 +/- 7.6 years) were enrolled in the study. Within 30 days of the CAS, 4 patients suffered from stroke, 1 patient suffered from a transient ischemic attack and 1 patient died. A new ischemic lesion on control brain MRI was detected in 34 (28.1%) patients. Using univariate and multivariate logistic regression analysis, no predictor (atherosclerotic plaque characteristics, history data, CAS data) was found to influence the risk of the onset of new brain ischemia. Conclusion: Characteristics of atherosclerotic plaque in the area of the internal carotid artery stenosis does not affect the risk of developing brain ischemia detected by brain MRI following CAS.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Česká a slovenská neurologie a neurochirurgie

  • ISSN

    1210-7859

  • e-ISSN

  • Volume of the periodical

    883

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    11

  • Pages from-to

    84-94

  • UT code for WoS article

    000514084800012

  • EID of the result in the Scopus database