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The flow of inhaled fibres in a model of the first bifurcation in human airways under transient conditions

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F22%3APU146660" target="_blank" >RIV/00216305:26210/22:PU146660 - isvavai.cz</a>

  • Result on the web

    <a href="http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2022.pdf" target="_blank" >http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2022.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The flow of inhaled fibres in a model of the first bifurcation in human airways under transient conditions

  • Original language description

    Inhaled fibres are known to induce various adverse health effects due to their ability to penetrate deep into the lower regions of the human lungs. This behaviour, however, could potentially be used for delivery of therapeutic drugs to alveoli. Such conversion of originally adverse behaviour to a beneficial and health-improving solution would be not only witty but also potentially commercially attractive. The reason why this potential has not been exploited so far grounds, besides other factors, also in the fact that our current mathematical or computational models are unable to precisely predict the delivered dose for a specific patient. Experimental data on the flow, orientation and “flips” of fibres are needed to improve the current mathematical models. This contribution presents the experimental setup and statistically evaluated data on the behaviour of rigid micrometre-sized fibres in the replica of the first bifurcation in human airways under transient conditions.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    20303 - Thermodynamics

Result continuities

  • Project

    <a href="/en/project/GA22-20357S" target="_blank" >GA22-20357S: Measurement and computational simulation of transport of fibrous aerosols in high velocity gradient flow and interaction of fibres with a wall</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů