The flow of inhaled fibres in a model of the first bifurcation in human airways under transient conditions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F22%3APU146660" target="_blank" >RIV/00216305:26210/22:PU146660 - isvavai.cz</a>
Result on the web
<a href="http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2022.pdf" target="_blank" >http://cas.icpf.cas.cz/download/Sbornik_VKCAS_2022.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The flow of inhaled fibres in a model of the first bifurcation in human airways under transient conditions
Original language description
Inhaled fibres are known to induce various adverse health effects due to their ability to penetrate deep into the lower regions of the human lungs. This behaviour, however, could potentially be used for delivery of therapeutic drugs to alveoli. Such conversion of originally adverse behaviour to a beneficial and health-improving solution would be not only witty but also potentially commercially attractive. The reason why this potential has not been exploited so far grounds, besides other factors, also in the fact that our current mathematical or computational models are unable to precisely predict the delivered dose for a specific patient. Experimental data on the flow, orientation and “flips” of fibres are needed to improve the current mathematical models. This contribution presents the experimental setup and statistically evaluated data on the behaviour of rigid micrometre-sized fibres in the replica of the first bifurcation in human airways under transient conditions.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
20303 - Thermodynamics
Result continuities
Project
<a href="/en/project/GA22-20357S" target="_blank" >GA22-20357S: Measurement and computational simulation of transport of fibrous aerosols in high velocity gradient flow and interaction of fibres with a wall</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů