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Toward Cartilage-Mimicking Biomaterials: Biotribological, Biochemical and Structural Evaluation of pHEMA and PVA-Based Hydrogels

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F26%3A0200519" target="_blank" >RIV/00216305:26210/26:0200519 - isvavai.cz</a>

  • Alternative codes found

    RIV/70883521:28610/25:63597358

  • Result on the web

    <a href="https://pubs.acs.org/doi/10.1021/acsomega.5c10283" target="_blank" >https://pubs.acs.org/doi/10.1021/acsomega.5c10283</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1021/acsomega.5c10283" target="_blank" >10.1021/acsomega.5c10283</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Toward Cartilage-Mimicking Biomaterials: Biotribological, Biochemical and Structural Evaluation of pHEMA and PVA-Based Hydrogels

  • Original language description

    This study compares the biotribological and structural behavior of PVA and pHEMA hydrogels under conditions simulating the cartilage environment to understand the lubrication mechanisms. PVA samples exhibited very low apparent friction coefficients and high-water uptake due to their hydrophilic, hydroxyl-rich network. In contrast, pHEMA hydrogels showed higher friction but substantially enhanced wear resistance, particularly under extended sliding against rough counterfaces. While PVA offers excellent lubrication performance, its wear stability remains limited. On the other hand, the low wear observed in pHEMA-despite its higher friction-suggests strong structural resilience, making it a promising platform for further tailoring toward cartilage-mimicking applications. The results highlight the importance of balancing interfacial lubrication and mechanical durability when designing hydrogel-based cartilage replacements.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20300 - Mechanical engineering

Result continuities

  • Project

    <a href="/en/project/EH22_008%2F0004634" target="_blank" >EH22_008/0004634: Mechanical engineering of biological and bio-inspired systems</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    ACS Omega

  • ISSN

    2470-1343

  • e-ISSN

    2470-1343

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    51

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    14

  • Pages from-to

    63441-63454

  • UT code for WoS article

    001632722700001

  • EID of the result in the Scopus database

    2-s2.0-105026109454