Ecg Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F05%3APU52787" target="_blank" >RIV/00216305:26220/05:PU52787 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/05:00013328

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Ecg Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Original language description

The optical mapping of action potentials from heart surface is extensively used as a new possibility of non-invasive recording methods. It employs application of voltage-sensitive dyes (VSDs). Previously, VSDs has been successfully used in myocardial ischemia studies. Our previous Langendorff perfused heart experiments that have suggested shape changes in ECG signals in time and time-frequency domain caused by application of VSD di-4-ANEPPS during optical mapping. These changes went through detailed anaalysis to reveal impact to particular fractions of a heart cycle. The heart cycle was divided into three parts, corresponded to P-Q segments, QRS complexes, and ST-T segments. Dynamic time warping (DTW) is applied to all marked segments in each experimental period (control, loading and washout phase). Variability of ECG parts is measured by means of an optimal path resulting from DTW based on minimum distance between the control signal segments (before the application of VSD) and segment

Czech name

Ecg Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Czech description

The optical mapping of action potentials from heart surface is extensively used as a new possibility of non-invasive recording methods. It employs application of voltage-sensitive dyes (VSDs). Previously, VSDs has been successfully used in myocardial ischemia studies. Our previous Langendorff perfused heart experiments that have suggested shape changes in ECG signals in time and time-frequency domain caused by application of VSD di-4-ANEPPS during optical mapping. These changes went through detailed anaalysis to reveal impact to particular fractions of a heart cycle. The heart cycle was divided into three parts, corresponded to P-Q segments, QRS complexes, and ST-T segments. Dynamic time warping (DTW) is applied to all marked segments in each experimental period (control, loading and washout phase). Variability of ECG parts is measured by means of an optimal path resulting from DTW based on minimum distance between the control signal segments (before the application of VSD) and segment

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

JD - Use of computers, robotics and its application

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scripta medica

ISSN

1211-3395

e-ISSN

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Volume of the periodical

78

Issue of the periodical within the volume

6

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

273-280

UT code for WoS article

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EID of the result in the Scopus database

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