Specification and simplified analyzing data from MS/MS spectrometry

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F09%3APU81431" target="_blank" >RIV/00216305:26220/09:PU81431 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Specification and simplified analyzing data from MS/MS spectrometry

Original language description

The goal of this work was to design a suitable method for unifying score values from various identification tools of proteins identification in tandem mass spectrometry into a single score value. Output data from the mass spectrometric method were processed by two independent search tools Mascot and X!Tandem. Those were selected especially for their wide applications in proteomic laboratories. Results of both methods were evaluated through a newly designed function and unified to a single valued score that clearly identifies found proteins. The newly designed function of producing of scored values was termed Metascore and implemented into MATLAB computational environment. Given results were successfully tested on selected real data available in publicdatabases of proteomic sequences

Czech name

Specifikace identifikace dat z tandemové hmotnostní spektrometrie

Czech description

The goal of this work was to design a suitable method for unifying score values from various identification tools of proteins identification in tandem mass spectrometry into a single score value. Output data from the mass spectrometric method were processed by two independent search tools Mascot and X!Tandem. Those were selected especially for their wide applications in proteomic laboratories. Results of both methods were evaluated through a newly designed function and unified to a single valued score that clearly identifies found proteins. The newly designed function of producing of scored values was termed Metascore and implemented into MATLAB computational environment. Given results were successfully tested on selected real data available in publicdatabases of proteomic sequences

Type

D - Article in proceedings

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

<a href="/en/project/GD102%2F09%2FH083" target="_blank" >GD102/09/H083: Information Technology in Biomedical Engineering</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Proc. World Congress of Medical Physics and Biomedical Engineering

ISBN

978-3-642-03881-5

ISSN

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e-ISSN

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Number of pages

3

Pages from-to

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Publisher name

IFMBE

Place of publication

Neuveden

Event location

Mnichov

Event date

Sep 7, 2009

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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