Electrophysiological effects of Voltage-Sensitive Dye di-4-ANEPPS in Rabbit and Guinea Pig Isolated Heart
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F10%3APU87589" target="_blank" >RIV/00216305:26220/10:PU87589 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Electrophysiological effects of Voltage-Sensitive Dye di-4-ANEPPS in Rabbit and Guinea Pig Isolated Heart
Original language description
Voltage-sensitive dye (VSD) di-4-ANEPPS is currently used in our laboratory for recording of monophasic action potentials (MAPs) in isolated hearts. In this study, its electrophysiological effects on rabbit and guinea pig myocardium were compared duringstaining with VSD and washout from it. Electrograms were recorded and heart rate changes and the types and frequency of arrhythmias were evaluated. Althought certain electrophysiological changes were present in the hearts of both species, these changes are mostly reversible, especially in rabbit hearts. Thus, rabbit myocardium can be considered a reliable model for electrophysiological studies, especially when generation and propagation of the impulse is studied. It may be concluded that rabbit isolatedheart is more suitable model for electrophysiological studies in the isolated heart model than guinea pig heart.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
JD - Use of computers, robotics and its application
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA102%2F07%2F1473" target="_blank" >GA102/07/1473: Optical Methods for Registration of Heart Electrical Potentials and Calcium Concentration with Laser Stabilization</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Proceedings of Biosignal 2010: Analysis of Biomedical Signals and Images
ISBN
978-80-214-4106-4
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
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Publisher name
Brno University of Technology
Place of publication
Brno
Event location
Brno
Event date
Jun 27, 2010
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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