Influence of injection speed of contrast agent on perfusion analysis using fast bolus method

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F12%3APU100355" target="_blank" >RIV/00216305:26220/12:PU100355 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Influence of injection speed of contrast agent on perfusion analysis using fast bolus method
Original language description
Dynamic contrast enhanced ultrasound (DCE-US) imaging is a promising modality for noninvasive assessment of various tissue kinetic parameters (e.g. time-to-peak, mean transit time (MTT), blood flow etc.). These parameters can be used for diagnosis of pathological tissue functions caused by different diseases. Fast bolus method is based on the fast injection of bolus of contrast agent and repeated imaging with low MI to track contrast agent in tissue of interest (TOI) in time. Mathematical model fittingis an important part of this analysis, which usually presumes that injected bolus is infinitely short, but in practice this is impossible. The main aim of this paper is an analysis of influence of bolus injection rate on MTT estimated by different fitting model. We discover that using a finite-width bolus causes systematic error in MTT estimation.
Czech name
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Czech description
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Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Proceedings of the IEEE International Ultrasonics Symposium 2012, Dresden
ISBN
978-1-4577-1253-1
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
1319-1322
Publisher name
Neuveden
Place of publication
Neuveden
Event location
Dresden
Event date
Oct 7, 2012
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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