Perceptual Features as Markers of Parkinson’s Disease: The Issue of Clinical Interpretability

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F16%3APU118771" target="_blank" >RIV/00216305:26220/16:PU118771 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-319-28109-4_9" target="_blank" >http://dx.doi.org/10.1007/978-3-319-28109-4_9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-319-28109-4_9" target="_blank" >10.1007/978-3-319-28109-4_9</a>

Result language
angličtina
Original language name
Perceptual Features as Markers of Parkinson’s Disease: The Issue of Clinical Interpretability
Original language description
Up to 90 % of patients with Parkinson’s disease (PD) suffer from hypokinetic dysathria (HD) which is also manifested in the field of phonation. Clinical signs of HD like monoloudness, monopitch or hoarse voice are usually quantified by conventional clinical interpretable features (jitter, shimmer, harmonic-to-noise ratio, etc.). This paper provides large and robust insight into perceptual analysis of 5 Czech vowels of 84 PD patients and proves that despite the clinical inexplicability the perceptual features outperform the conventional ones, especially in terms of discrimination power (classification accuracy ACC=92 %, sensitivity SEN=93 %, specificity SPE=92 %) and partial correlation with clinical scores like UPDRS (Unified Parkinson’s disease rating scale), MMSE (Mini-mental state examination) or FOG (Freezing of gait questionnaire), where p < 0.0001.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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