EXPERIMENTAL USE OF NOVEL PULSE GENERATOR FOR IRREVERSIBLE ELECTROPORATION

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F17%3APU123515" target="_blank" >RIV/00216305:26220/17:PU123515 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
EXPERIMENTAL USE OF NOVEL PULSE GENERATOR FOR IRREVERSIBLE ELECTROPORATION
Original language description
Irreversible electroporation (IRE) is a relatively new technique for minimal invasive nonthermal ablation treatment of solid tumors. This article describes basics of IRE and available devices for this technique. The parameters of commercial NanoKnife IRE generator are verified and the unique experimental IRE generator developed at the Brno University of Technology is presented in this paper. Further, there is a comparison of thermal effects on a target tissue of commonly used radiofrequency ablation (RFA) and the novel IRE generator using an infrared camera. All experiments were performed ex vivo on a porcine liver. The difference in maximum temperature between the output powers used was 17.8 °C with RFA and 3 °C with IRE. This is a significant difference and shows the IRE’s capability of liver tissue ablation without thermal damage. The new IRE generator is also capable of replacing NanoKnife because of its features and versatility.
Czech name
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Czech description
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Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Proceedings of the 23nd Conference STUDENT EEICT 2017
ISBN
978-80-214-5496-5
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
568-572
Publisher name
Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních
Place of publication
první
Event location
Brno
Event date
Apr 27, 2017
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
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