All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Circadian Rhythms of Human Brain - Electrical Impedance

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F21%3APU142131" target="_blank" >RIV/00216305:26220/21:PU142131 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Circadian Rhythms of Human Brain - Electrical Impedance

  • Original language description

    Rationale: Long-term data collection using implantable neural sense and stimulation (INSS) devices in patients with epilepsy enables investigation of ultradian, circadian and infradian rhythms in sleep, seizures, interictal epileptiform discharges (IED), and brain impedance. It has long been recognized that IED and seizures have circadian patterns. Recent studies also highlight the importance of circadian changes in brain extracellular space, and the functional role of slow-wave sleep and the associated increase in extracellular space volume that is hypothesized to provide improved metabolite and protein clearance. The direct evidence for increased extracellular space volume during sleep primarily comes from rodent studies, and a few human imaging studies with limited temporal sampling. Here we investigate a potential surrogate of extracellular volume, the brain electrical impedance in hippocampus (HPC) and anterior nucleus of thalamus (ANT) over multiple months in four ambulatory humans with drug res

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů