Long-Term Effect of Repetitive Transcranial Magnetic Stimulation on Parkinson’s Disease Patients with Different Severity of Hypokinetic Dysarthria
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F24%3APU151656" target="_blank" >RIV/00216305:26220/24:PU151656 - isvavai.cz</a>
Result on the web
<a href="https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2024_sbornik_2.pdf" target="_blank" >https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2024_sbornik_2.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.13164/eeict.2024.151" target="_blank" >10.13164/eeict.2024.151</a>
Alternative languages
Result language
angličtina
Original language name
Long-Term Effect of Repetitive Transcranial Magnetic Stimulation on Parkinson’s Disease Patients with Different Severity of Hypokinetic Dysarthria
Original language description
The prevalence of Parkinson’s disease (PD), severe neurodegenerative disorder, has steadily increased. Among the symptoms of PD is hypokinetic dysarthria (HD), a motor speech disorder, characterised by respiratory, articulatory, prosodic and phonatory impairments. It has been demonstrated that both motor and non-motor symptoms of PD can be improved using the repetitive Transcranial Magnetic Stimulation (rTMS). This study analyses acoustic speech characteristics of 19 participants diagnosed with PD before (one pre-stimulus) and after (four poststimulus) evaluation sessions of rTMS treatment. The participants were divided into two groups – receiving either rTMS or sham stimulation (1:1 randomization). Based on the prestimulus subresults of the Test 3F, participants were stratified into two cohorts, according to their possible HD severity level. Speech recordings were also taken during each evaluation session. The outcome of the follow-up acoustic analysis resulted in 16 parameters for each of those sessions. Their evaluation demonstrated the dependence of the effect of rTMS treatment on the severity level. The actively stimulated group of the first cohort showed consistent improvement in articulation and prosody (sham did not) while the actively stimulated group of the second stratified cohort showed consistent improvement in phonation (sham did not). The study provides early preliminary insights into the benefits of rTMS for the alleviation of HD manifestations (symptomatic treatment of PD). In addition, it provides new insights into the possible relationship between the effectiveness of rTMS and the degree of severity in HD.
Czech name
—
Czech description
—
Classification
Type
D - Article in proceedings
CEP classification
—
OECD FORD branch
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Result continuities
Project
<a href="/en/project/LX22NPO5107" target="_blank" >LX22NPO5107: National institute for Neurological Research</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Proceedings II of the 30th Conference STUDENT EEICT 2024 Selected Papers
ISBN
978-80-214-6230-4
ISSN
2788-1334
e-ISSN
—
Number of pages
5
Pages from-to
151-155
Publisher name
Brno University of Technology, Faculty of Electrical Engineering and Communication
Place of publication
Brno
Event location
Brno
Event date
Apr 23, 2024
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
—