A low-cost picowatt calorimeter using a flexible printed circuit board

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F25%3APU156156" target="_blank" >RIV/00216305:26220/25:PU156156 - isvavai.cz</a>
Result on the web
<a href="https://www.nature.com/articles/s41467-025-58025-9" target="_blank" >https://www.nature.com/articles/s41467-025-58025-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41467-025-58025-9" target="_blank" >10.1038/s41467-025-58025-9</a>

Result language
angličtina
Original language name
A low-cost picowatt calorimeter using a flexible printed circuit board
Original language description
Calorimetry is crucial in biology, chemistry, physics, and pharmaceutical research, enabling the detection of heat changes at nanowatt and picowatt levels. However, traditional calorimetry systems are often limited by high costs and complex fabrication processes. Here, we reduce the cost and fabrication complexity of microcalorimeters by utilizing widely available flexible printed circuit manufacturing processes. This device achieves temperature and power resolutions of ≈ 6 μK and ≈ 654 pW in vacuum. Its feasibility is validated across a wide range of measurements, including salt crystallization, protein crystallization, and cellular metabolism. Our concept enhances the accessibility of microcalorimeters for high-resolution thermal analysis, which is challenging for conventional calorimeters.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20901 - Industrial biotechnology

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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