Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F26%3A0197697" target="_blank" >RIV/00216305:26220/26:0197697 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/25:00143873 RIV/00159816:_____/25:00082454
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/jbio.202400494" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/jbio.202400494</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jbio.202400494" target="_blank" >10.1002/jbio.202400494</a>

Result language
angličtina
Original language name
Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli
Original language description
This paper describes a compact video-ophthalmoscope (VO) designed for capturing retinal video sequences of the optic nerve head (ONH) under flicker light stimulation. The device uses an OLED display and a fiber optic-coupled LED light source, enabling high-frame-rate video at low illumination intensity (12 mu W/cm2). Retinal responses were recorded in 10 healthy subjects during flicker light exposure with a pupil irradiance of 2 mu W/cm2. Following 20 s of stimulation, all subjects displayed changes in retinal reflectance and pulsation attenuation, linked to blood flow and volume variations. These findings suggest that increased blood volume leads to decreased retinal reflectance. Temporal analysis confirmed the ability to capture flicker-induced retinal reflectance changes, indicating its potential for spatial and temporal analysis. Overall, this device offers a portable approach for investigating dynamic retinal responses to light stimuli, which can aid the diagnosis of retinal diseases like diabetic retinopathy, glaucoma, or neurodegenerative diseases affecting retinal blood circulation.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20601 - Medical engineering

Project
<a href="/en/project/GA21-18578S" target="_blank" >GA21-18578S: Dual-wavelength functional retinal imaging and simultaneous biosignals acquisition for ocular blood circulation assessment</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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