Characterization and degradation behaviour of biocompatible triblock copolymer

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F06%3APU63803" target="_blank" >RIV/00216305:26310/06:PU63803 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Characterization and degradation behaviour of biocompatible triblock copolymer

Original language description

Poly(lactic acid) and poly(glycolic acid) have been under extensive study since they were introduced as biodegradable polymers having hydrolytically unstable backbones. Therefore, these biopolymers can be used for a certain type of biomedical applicationsuch as injectable polymer drug delivery systems, tissue implants or resorbable bone adhesives. The prevailing mechanism for the biopolymer degradation is a simple random chemical hydrolysis. This work is focused on the studying of the thermoreversiblebehaviours of two copolymers, PLGA-PEG-PLGA and the same but modified with itaconic acid (ITA-PLGA-PEG-PLGA-ITA).

Czech name

Charakterizace a studium průběhu degradace biokompatibilního triblok kopolymeru

Czech description

Poly(lactic acid) and poly(glycolic acid) byly v minulých letech intenzivně studovány pro využití v oblasti medicíny. Tyto polymery mají hydrolyticky nestabilní vyzby a dochází tedy k jejich samovolné degradaci. Proto jsou používány jako injektovatelné nosiče léků, tkáňové implantáty nebo resorbovatelné pojivo kostí.

Type

A - Audiovisual production

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

ISBN

80-214-3320-5

Place of publication

Brno, Czech Republic

Publisher/client name

Faculty of Chemistry

Version

+1

Carrier ID

neuvedeno