Nanoparticles formed by self-assembly of negatively charged hyaluronan and cationic surfactant

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F13%3APU119916" target="_blank" >RIV/00216305:26310/13:PU119916 - isvavai.cz</a>
Result on the web
<a href="http://konsys-t.tanger.cz/files/proceedings/14/reports/1926.pdf" target="_blank" >http://konsys-t.tanger.cz/files/proceedings/14/reports/1926.pdf</a>
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Nanoparticles formed by self-assembly of negatively charged hyaluronan and cationic surfactant
Original language description
Physico-chemical interactions in hyaluronan-surfactant system result in nanoparticles formation which can be used in targeted delivery of hydrophobic active substances. The aim of our study was to prepare hyaluronic acid nanoparticles based on electrostatic interactions with oppositely charged molecules. Particles were investigated using dynamic light scattering and Laser Doppler Velocimetry methods. Size distribution and zeta potential measurement were utilized to explore the formation of complex micelles. Particles size distributions depend on type of solvent, molecular weight of hyaluronan and charge ratio of components of the hyaluronan-surfactant system. Aggregates formation is influenced by preparation of the system. Stability of the micellar particles depends on zeta potential value.
Czech name
—
Czech description
—

Project
<a href="/en/project/LD12068" target="_blank" >LD12068: Preparation of hyaluronan-micellar-aggregate colloids for nanomedical applications and characterization of their properties</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)