Study of Nanoparticles Formed by Negatively Charged Hyaluronan and Cationic Surfactant
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F14%3APU109242" target="_blank" >RIV/00216305:26310/14:PU109242 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Study of Nanoparticles Formed by Negatively Charged Hyaluronan and Cationic Surfactant
Original language description
Negatively charged hyaluronan binds to cationic surfactant via electrostatic interactions which result in self-assembly nanoparticles formation. The aim of study was to prepare and study hyaluronic acid nanoparticles based on electrostatic interactions with oppositely charged surfactant molecules. Aggregates formation is influenced by preparation of systems. Different types of particles are formed if hyaluronan is added to surfactant solution or vice versa. If hyaluronan have a role of titrant, final particles are smaller than in the case of surfactant as titrant and can be more suitable for drug delivery applications. Assuming in the isoelectric point is reached compensation of charges of hyaluronan and surfactant, real degrees of hyaluronan dissociation were determined. Concentration of hyaluronan and conformation of hyaluronan in the system have a significant effect on established degree of dissociation.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LD12068" target="_blank" >LD12068: Preparation of hyaluronan-micellar-aggregate colloids for nanomedical applications and characterization of their properties</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
XIV. pracovní setkání fyzikálních chemiků a elektrochemiků, sborník příspěvků
ISBN
978-80-210-6842-1
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
73-77
Publisher name
Neuveden
Place of publication
Neuveden
Event location
Masarykova Universita, Brno
Event date
Jun 3, 2014
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
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