UPLC-MS/MS method for quantification of eight major ergot alkaloids and their corresponding epimers in feed

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F14%3APU112268" target="_blank" >RIV/00216305:26310/14:PU112268 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
UPLC-MS/MS method for quantification of eight major ergot alkaloids and their corresponding epimers in feed
Original language description
Ergot alkaloids are mycotoxins produced predominantly by fungi of the Claviceps genus, which mainly affect cereals and wild grasses. Ingestion of ergot alkaloids can cause severe health problems in humans and animals. Thus, there is a need for methods that allow determination of these dangerous toxins. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for the simultaneous determination of eight ergot alkaloids: ergosine, ergocornine, ergocryptine and ergocristine andtheir corresponding epimers as well. Mean recovery, precision, matrix effects and limits of quantification (LOQ) have been assessed for cereal and grass matrices within the method validation. Sample preparation has been based on modified QuEChERS approach. The presented method was used to inspect various feed samples. Ergot alkaloids were found in 31 out of 113 samples investigated. Ergocornine was the most frequently occuring alkaloid, while the highest levels were observed for ergocryp
Czech name
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Czech description
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Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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